Breath analysis. Physiological basis and sampling techniques.

Physiological Modeling for Analysis of Exhaled Breath

Due to its broad scope and applicability, breath gas analysis holds great promise as a versatile framework for general bio-monitoring applications. As a biochemical probe, volatile organic compounds (VOCs) in exhaled breath are unique in the sense that they can provide both non-invasive and continuous information on the metabolic and physiological state of an individual. Apart from diagnostics ...

Analytical and Physiological Specificity Issues in Breath Alcohol Analysis

Drink-drivers frequently allege that their breath alcohol reading was so high because some non-ethanolic chemical was in their breath at the time of the test. This paper reviews the author’s experiences and methodology in dealing with such matters in the British Courts on behalf of the Police. Conceivable sources of breath contaminants are ingestion (with food, medication or smoking), endogenou...

Methodological and physiological aspects of exhaled breath analysis

Breath Analysis Using Laser Spectroscopic Techniques: Breath Biomarkers, Spectral Fingerprints, and Detection Limits

Breath analysis, a promising new field of medicine and medical instrumentation, potentially offers noninvasive, real-time, and point-of-care (POC) disease diagnostics and metabolic status monitoring. Numerous breath biomarkers have been detected and quantified so far by using the GC-MS technique. Recent advances in laser spectroscopic techniques and laser sources have driven breath analysis to ...

Optimisation of sampling parameters for standardised exhaled breath sampling.

The lack of standardisation of breath sampling is a major contributing factor to the poor repeatability of results and hence represents a barrier to the adoption of breath tests in clinical practice. On-line and bag breath sampling have advantages but do not suit multicentre clinical studies whereas storage and robust transport are essential for the conduct of wide-scale studies. Several device...